… Along with the recent progress in dissecting the differentiation pathways of early B-lymphoid
differentiation, information on the role of transcription factors in regulating early stages has …

… B-cell differentiation [2,3,4]. Furthermore, it is now evident that the same mechanisms that
control normal B-lymphoid development in mice and humans are targeted in B-lymphoid …

… expression of multiple B-lymphoid genes including RAG1 and … differentiate into CD4 + CD8
+ T cells upon co-culture with Delta-1-expressing stromal cells (115, 116). In complementary …

… In this review, we focus principally on the regulation of differentiation and functional … Origins
of and fate potential for mature B lymphoid cells. Shown is a simplified outline of the broad …

… of EBF1 by ZNF521 does take place in B-lymphoid cells. To further pursue this observation,
… EBF1 target genes in B-lymphoid cells. Therefore, in a complementary approach we used …

… differentiate from hematopoietic stem cells through a series of distinct stages. Early B cell …
of CD10 corresponds to expression of B lymphoid related transcription factors and markers, as …

… [11, 35, 37], and recent data show that EBF complements specific … first discuss current
understanding of the mechanisms responsible for suppressing alternative fate differentiation …

… The differentiation of B cells from multipotent haematopoietic … lymphoid (ALP) and B-lymphoid
committed (BLP) progenitors … binding of complementary cis-gene regulatory elements …

… that poise the genes for expression at subsequent stages of differentiation. Poised chromatin
… In a complementary set of experiments, we isolated pro-B cells from mice carrying one or …

… for their differentiation [23], elegant experiments confirmed that the myeloid versus B lymphoid
… These data provided one of the earliest examples of the control of differentiation outcomes …